Chicago scored four in the first inning at Daikin Park, and Houston has already made two errors. The White Sox lead the American League Wild Card Series 1-0 and can advance with a win.

Sam Antonacci doubled to open the game and scored on a Kyle Teel single. Andrew Benintendi drove in two more on a single that Lucas Spence misplayed in center. Tristan Peters singled home a fourth. Hunter Brown was pulled with two outs in the first after a wild pitch and a walk.

First pitch was 5 p.m. ET. The game streams on Peacock and airs on NBC Sports Network, which is available through YouTube TV, Fubo and Xfinity. Spanish coverage is on Universo with Univision Radio providing Spanish audio. ESPN Radio has national coverage.

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Chicago White Sox's Andrew Benintendi is congratulated in the dugout after scoring in the sixthinning of a baseball game against the Cleveland Guardians in Cleveland, Monday, Sept. 14, 2026. — (AP Photo/Sue Ogrocki)

Sean Burke starts for Chicago at 11-7 with a 3.34 ERA and 185 strikeouts over 172 1/3 innings. Hunter Brown started for Houston at 6-4 with a 3.19 ERA. Brown is 2-0 with a 1.38 ERA in two starts against the White Sox this season and had a 2.45 ERA over his final six starts.

Chicago lineup: Sam Antonacci LF, Kyle Teel C, Miguel Vargas 3B, Munetaka Murakami 1B, Andrew Benintendi DH, Tristan Peters CF, Chase Meidroth 2B, Braden Montgomery RF, Colson Montgomery SS.

Chicago White Sox's Munetaka Murakami adjusts his cap
Chicago White Sox's Munetaka Murakami adjusts his cap during batting practice before Game 2 of baseball's American League Wild Card Series against the Chicago White Sox, Wednesday, Sept. 30, 2026, in Houston. — (AP Photo/Karen Warren)

Houston lineup: Jeremy Pena SS, Yordan Alvarez LF, Isaac Paredes DH, Jose Altuve 2B, Yainer Diaz C, Christian Walker 1B, Lucas Spence CF, Cam Smith RF, Nick Allen 3B.

Chicago won Game 1. White Sox doubled them. 3 x 3 equal six, that's for you. 6-3 on Tuesday. Sam Antonacci drove in two with a single in the second and Colson Montgomery homered 432 feet in the fourth. Nelson Velazquez homered for Houston.

The loss was Houston's eighth straight at home in the postseason, dating to Game 1 of the 2023 Division Series.

Chicago is trying for its first playoff series win since the 2005 World Series, which it swept from Houston in the same ballpark. A win also sends the White Sox to the Division Series for the first time since 2021.

Visiting teams that win Game 1 have taken 12 of 15 wild card series, including nine sweeps. The exception came last year when the Yankees lost the opener at home to Boston and came back.

Houston used eight relievers in Game 1, and four may be unavailable on workload. Josh Hader, Bryan Abreu and Bennett Sousa each threw fewer than 15 pitches. Left-hander Steven Okert is out for the series with a hamstring strain.

If Houston wins, Game 3 is Thursday at Daikin Park. The winner faces Cleveland, which earned a bye as the No. 2 seed.

In the earlier game, Philadelphia beat Atlanta 4-3 in 10 innings to force a Game 3. Kyle Schwarber and Bryce Harper hit back-to-back home runs in the eighth to tie it, and Alec Bohm homered in the 10th. Andrew Painter got the win and Didier Fuentes took the loss.

Two other elimination games follow Wednesday. New York leads Boston 1-0 and plays at 8 p.m. ET on NBC. San Diego leads Chicago 1-0 and plays at 10 p.m. ET on Peacock and NBC Sports Network.